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Genotypic Inference of HIV-1 Tropism Using Population-based Sequencing of V3
Published on: December 28, 2010
2000年から2004年までのインド南部の若年成人におけるHIV-1の傾向:流行研究
Rajesh Kumar1, Prabhat Jha, Paul Arora
1School of Public Health, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Lancet (London, England)
|April 18, 2006
まとめ
HIV-1の罹患率は,2000~04年の間に南インドの若い女性の3分の1以上大幅に減少しました. このヒト免疫不全ウイルス1型 (HIV-1) の減少は,コンドームの使用の増加による可能性があり,継続的な予防プログラムの必要性を強調しています.
科学分野:
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
- 感染症の研究 感染症の研究
背景:
- インドは,特に南部の州で,HIV-1の流行率が増加すると予測されています.
- インシデント感染の追跡は,疫病の動態を理解するために不可欠です.
- 産前と性感染症の診療所に通う若年人口は,HIV-1発生率を推定するために研究されました.
研究 の 目的:
- 若者におけるHIV-1感染率を調査することでHIV-1感染率を推定する.
- インドの産前およびSTIクリニック参加者のHIV-1流行の傾向を分析する.
- インド南部の州と北部の州間のHIV-1感染率と傾向を比較する.
主な方法:
- 294,050人の女性と58,790人の男性から得られた,無関連で匿名化されたHIV-1感染率のデータを分析した.
- 産前診療所216所,性感染症診療所132所から2000年04月までの間に収集したデータ.
- インド南部の州と北部州のデータを別々に分析した.
主要な成果:
- 南部の若い女性 (15歳から24歳) のHIV-1感染率は,2000年から2004年にかけて35% (1.7%から1.1%) 減少した.
- 北部の州では,高齢女性 (25-34歳) やどの年齢層でも有意な減少は見られなかった.
- 南部のSTI診療所に通う若者,すなわちSTIを患っている若者における罹患率は減少した.
結論:
- 南インドの若い女性のHIV-1感染率の3分の1を超える減少は,データによって支持されています.
- 男性とセックスワーカーの間でコンドームの使用の増加は,感染の減少の要因である可能性が高い.
- セックスワーカーのためのピアベースのコンドームと教育プログラムの拡大は,インドのHIV-1制御に不可欠です.
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