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Updated: Jul 17, 2026

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
07:16

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Published on: August 16, 2018

微小分子による Gbetagammaサブユニットのシグナル伝達の微分ターゲティング

Tabetha M Bonacci1, Jennifer L Mathews, Chujun Yuan

  • 1Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

Science (New York, N.Y.)
|April 22, 2006
PubMed
まとめ

研究者らは,Gタンパク質ベタガマサブユニットを選択的に標的にする小分子を特定した. このアプローチは,Gタンパク質結合受容体のシグナル伝達を調節し,様々な疾患に対する潜在的な治療戦略を提供します.

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BRET-based G Protein Biosensors for Measuring G Protein-Coupled Receptor Activity in Live Cells09:21

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