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Updated: May 10, 2026

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers
08:28

Single-molecule Manipulation of G-quadruplexes by Magnetic Tweezers

Published on: September 19, 2017

クアドルプレックス折り畳みを設計する: 核酸化物の構成は,グアニン四重複合体の折り畳みのトポロジーと分子性を決定する

Chung-Fei Tang1, Richard H Shafer

  • 1Department of Pharmaceutical Chemistry, School of Pharmacy and Graduate Group in Chemistry and Chemical Biology, University of California, San Francisco, California 94143-0446, USA.

Journal of the American Chemical Society
|April 28, 2006
PubMed
まとめ

核酸四重複折り畳みトポロジーは,グアニン核酸化物構成によって制御されます. DNAデオキシグアノシン (dG) の代わりにRNAグアノシン (rG) を代用すると,折り畳みを逆転させ,分子性を変化させることができます.

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