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Updated: May 1, 2026

Optimized Protocol for the Extraction of Proteins from the Human Mitral Valve
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TMP21はプレシニリン複合体の成分で,ガンマ分泌酵素を調節するが,エプシロン分泌酵素の活性を調節しない

Fusheng Chen1, Hiroshi Hasegawa, Gerold Schmitt-Ulms

  • 1Department of Medicine, and Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada M5S 3H2.

Nature
|April 28, 2006
PubMed
まとめ

プレセニリン複合体は,タンパク質の分裂を調節する. 研究者らは,p24ファミリーのメンバーであるTMP21が,これらの複合体を結合し,エプシロン分泌酵素に影響を与えることなく,ガンマ分泌酵素の活性を特異的に調節することを発見した.

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