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Updated: May 6, 2026

Analyzing the Function of Small GTPases by Microinjection of Plasmids into Polarized Epithelial Cells
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Published on: May 31, 2011

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Rich1/Amot複合体は,上皮細胞のCdc42 GTPaseとアピカル極性タンパク質を調節する

Clark D Wells1, James P Fawcett, Andreas Traweger

  • 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON M5G 1X5, Canada.

Cell
|May 9, 2006
PubMed
まとめ

研究者らは,Cdc42 GTPアゼを調節するタンパク質ネットワークを特定し,これは上皮細胞の頂点極性および緊密な接合の整合性にとって重要である. このネットワークには,Rich1,アンジオモチン (Amot) と重要な結合タンパク質が関与し,細胞構造と密輸を調整します.

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