人口ベースの化学療法における用量決定のために修正されたスケール.
1Department of Epidemiology and Population Sciences, London School of Hygiene and Tropical Medicine, UK.
Lancet (London, England)
|January 26, 1991
まとめ
特殊な秤はガンビアにおけるスキストソミアシスの制御を簡素化し,医療従事者がプラジクアンテルとメトリフォナートを簡単に投与できるようにしました. このアプローチにより,必要不可欠な治療のコミュニティーで高いカバー率を達成しました.
科学分野:
- 公衆衛生は公衆衛生である.
- トロピカル・メディシン (熱帯医学)
- 医薬品科学 医薬品科学とは
背景:
- 統合失調症の制御プログラムには,資源の限られた環境で効果的な薬剤投与が必要です.
- プライマリヘルスケアへの統合は,地域保健医療従事者のための簡素化されたプロトコルを必要とします.
研究 の 目的:
- 薬剤の投与量を簡素化するための特殊な秤の有効性を評価する. スキストソミアシス制御.
- プラジクォンテールとメトリフォナートに対するコミュニティのカバー率を,新しい重量スケールシステムを用いて評価する.
主な方法:
- プラジクアンテルとメトリフォナートのための直接的な錠剤読み取りの秤の開発と実装.
- 半文盲の医療従事者を利用して,体重で決定された錠剤数に基づいて薬を投与する.
- 秤の横にシンプルな記録システムの統合.
主要な成果:
- 高い被覆率を達成:単一投与のプラジクォンテルの場合,最大97%まで.
- マルチドースメトリホネートの有意なカバー率: 2ヶ月間に 82.4% .
- タブレットスケールは,実装と適応が容易であることが判明しました.
結論:
- 特殊な体重計は,スキストソミアシス制御における薬剤投与を簡素化するための効果的なツールです.
- この方法は,大量薬物投与における初等保健医療従事者の能力を高めます.
- このアプローチは,ガンビアで高い範囲と実現可能性を示した.
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