免疫学:トール型受容体と抗体反応
1Department of Immunology, The Scripps Research Institute, La Jolla, California 92037, USA.
Nature
|May 20, 2006
まとめ
トール型受容体 (TLR) のシグナル伝達は,強固な抗体生成に不可欠ではありません. 免疫反応は,TLRの活性化なしでも,効果的な抗体生成を生成することができ,ワクチン設計に影響を与えます.
科学分野:
- 免疫学 免疫学とは
- 微生物学 微生物学とは
- ワクチン学 ワクチン学
背景:
- リポポリサッカリドのような微生物の成分は,トール型受容体 (TLRs) を活性化させ,免疫反応を増強します.
- 以前の研究によると,TLRシグナリングは,T依存抗体生成を含む適応免疫の開始と維持に不可欠である.
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