水熱噴出孔管虫における水平エンドシンビオント伝播
Andrea D Nussbaumer1, Charles R Fisher, Monika Bright
1Department of Marine Biology, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria.
Nature
|May 20, 2006
まとめ
熱水噴出管線虫は,定着した後,皮膚を通して必要不可欠な細菌共生体を取得します. このプロセスは,特化した臓器であるトロフォソームを確立し,宿主が成熟するにつれて停止します.
科学分野:
- マリン・バイオロジー マリン・バイオロジー
- シンビオシス研究研究
- 発達生物学 発達生物学とは
背景:
- 強制的な細菌共生体は,熱水噴出孔管虫を含む多くの宿主の生存に不可欠です.
- 熱水噴出孔管虫の幼虫は,最初は共生体なしであり,一時的な消化器系を発展させ, symbiontの取得を定着後必要とする.
- 大人のチューブワームは,栄養のために完全に細菌の共生体に依存しており,世代間の共生体の伝播が不可欠です.
研究 の 目的:
- 水熱噴出孔管虫における共生体獲得のメカニズムを解明する.
- シンバイオントを収容する臓器であるトロフォソームの発達を記述する.
- ホストの発達とシンビオントの植民地化との相互作用を理解する.
主な方法:
- チューブワームの幼虫と幼虫に関する観察研究.
- シンビオントの侵入とトロフォソームの形成を追跡するための顕微鏡分析.
- 発達中の宿主組織の組織学的検査.
主要な成果:
- バクテリアの共生体は,幼虫管を植民地化し,皮膚を通って管虫宿主に侵入します.
- シンビオントの植民地化は,幼稚期の初期に起こり,メソダーマ組織からトロフォソームの発達と一致します.
- 後期の青年期における宿主組織 (表皮,筋肉) の大量アポトーシスは,共生生物の植民地化の停止と相関する.
結論:
- チューブワームのシンビオント獲得は,幼虫の定着後に開始される皮膚ベースのプロセスです.
- トロフォソームの発達は,シンビオントの植民地化のタイミングと停止と密接に関連しています.
- この研究は,共生体獲得のモデルを提供し,相互性および病原性双方の関係に適用可能な宿主-微生物相互作用の洞察を提供します.
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