Cyld,Bcl-3NF-kappaB,

Ramin Massoumi1, Katarzyna Chmielarska, Katharina Hennecke

  • 1Department of Molecular Medicine, Max Planck Institute of Biochemistry, D-82152 Martinsried, Germany.

Cell
|May 23, 2006
PubMed
まとめ

CYLD遺伝子のデウビキチナゼは,異なるNF-kappaB経路を制御することによって,皮膚腫瘍の成長を調節する. CYLDの喪失は,細胞増殖に影響することで,化学的に誘発された皮膚腫瘍に対する感受性を高めます.

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