関連する実験動画

Updated: May 3, 2026

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells
10:06

Engineering Artificial Factors to Specifically Manipulate Alternative Splicing in Human Cells

Published on: April 26, 2017

8.3K

ヒストンH2BモノウビキチネーションはFACTと連携して機能し,RNAポリメラーゼIIによる延長を調節する

Rushad Pavri1, Bing Zhu, Guohong Li

  • 1Howard Hughes Medical Institute, Department of Biochemistry, Division of Nucleic Acids Enzymology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, 683 Hoes Lane, Piscataway, NJ 08854, USA.

Cell
|May 23, 2006
PubMed
まとめ

転写活性のマーカーであるヒストンH2Bモノビキチネーションは,RNF20/40とUbcH6.6によって確立されています. このプロセスは,クロマチンを介してRNAポリメラーゼIIの延長を促進する転写因子を必要とします.

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Histone Modification

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