角膜外体除去後の角膜の治癒におけるアイパッドの有効性
1Department of Ophthalmology, St James's University Hospital, Leeds, UK.
Lancet (London, England)
|March 16, 1991
まとめ
角膜の異体除去後にアイパッドを適用すると,治癒の利点がなく,不快感が増加します. クロランフェニコルの単独治療は,角膜上皮質の欠陥に対するアイパッドと同じくらい効果的です.
科学分野:
- オフタルモロジック (眼科)
- 角膜疾患の治療 角膜疾患の治療
- 傷の癒し 傷の癒し
背景:
- 角膜上皮質の欠陥は,角膜の異体除去後に一般的に発生します.
- 標準的な術後のケアには,しばしばアイパッドの適用が含まれます.
研究 の 目的:
- 角膜上皮質の欠陥の治療にクロラムフェニコルと併用して使用するアイパッドの有効性を評価する.
- イヤパッドの使用に関連する患者の快適性のレベルを評価するために.
主な方法:
- 角膜上皮質の欠陥を有する30人の患者を含むランダム化制御試験.
- 患者はクロランフェニコルを眼パッドで投与するか,クロランフェニコルを単独で投与した.
- 角膜の治癒と患者の不快感は24時間および48時間後に監視されました.
主要な成果:
- 角膜の欠陥はすべて,統計的に有意な違いはなく,両方のグループで48時間以内に治りました.
- クロランフェニコルと眼パッドを併用したグループと,クロランフェニコル単独投与群の治癒率の有意な差は認められなかった.
- 眼パッドを使用した患者は24時間後により大きな不快感を報告しました.
結論:
- イヤパッドの適用は,外体除去後の角膜上皮質の欠陥の治癒を促進しません.
- この文脈でのアイパッドの使用は,患者の不快感の増加と関連しています.
- クロランフェニコル治療だけでは十分で,これらの角膜欠陥の管理にはより快適です.
関連する概念動画
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Accessory Structures of the Eye
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Ophthalmic Drug Delivery Systems
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
Microbiome of the Eye
The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...


