のコミュニティ対策:パーメトリンクリームの使用に基づくモデル
D Taplin1, S L Porcelain, T L Meinking
1Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida.
Lancet (London, England)
|April 27, 1991
まとめ
パナマ諸島での疹の発生は,パーメトリン5%クリームを使用して効果的に制御され,古い治療法が失敗したときに有効性を実証しました. 持続的なコントロールには,低水準のの流行を維持するために継続的な監視と治療が必要でした.
科学分野:
- エピデミオロジー エピデミオロジー
- 皮膚科 皮膚科について
- トロピカル・メディシン (熱帯医学)
背景:
- パナマのクナ族インディアンでは,リンダーンとクロタミトンの治療にも関わらず,疹の流行が18年間続いた.
- 以前の治療法では,サンブラス諸島におけるの流行を抑制することができなかった.
研究 の 目的:
- ペルメトリン5%クリームのエピデミックのコントロールにおける有効性を評価する.
- ペルメトリン治療の scabies 流行および二次細菌感染症に対する長期的な影響を評価する.
主な方法:
- パーメトリン5%クリームを使用した地域全体の治療プログラムが,756人の住民の島で実施されました.
- 介入前,介入中,および介入後,治療中断およびコントロールの喪失の期間を含む,の流行をモニタリングしました.
- 細菌性皮膚感染症もモニタリングされた.
主要な成果:
- パーメトリン5%クリームによる大量治療後,疹の罹患率は33%から1%未満に減少しました.
- 持続的な低罹患率 (<1.5%) は,継続的な監視と治療で3年以上にわたって維持されました.
- 3週間の投与中断で3.6%に増加し,コントロールを失った後に12%に増加した.
- 細菌性皮膚感染症は,のコントロールによって著しく減少しました.
結論:
- パーメトリン5%クリームは,リンダーンに耐性のある地域でも,安全で非常に効果的な治療です.
- 継続的な監視と迅速な治療は,長期にわたるのコントロールを維持するために不可欠です.
- 効果的なの管理は,二次性細菌性皮膚感染症の減少につながる可能性があります.
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