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Updated: Jul 19, 2026

Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models
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Induction of Protein Deletion Through In Utero Electroporation to Define Deficits in Neuronal Migration in Transgenic Models

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I-POU:POUドメインのタンパク質で,ニューロン特異的な遺伝子活性化を阻害する

M N Treacy1, X He, M G Rosenfeld

  • 1Eukaryotic Regulatory Biology Program, University of California, San Diego School of Medicine, La Jolla 92093-0648.

Nature
|April 18, 1991
PubMed
まとめ

新種のタンパク質であるI-POUは,別のタンパク質であるCf1-a.と結合することで,神経細胞の遺伝子活性化を抑制する. この発見は,発達中の遺伝子発現を制御するための新しいメカニズムを明らかにしています.

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