大規模な腹部外科手術後の胆石形成
1Department of Surgery, Westmead Hospital, New South Wales, Australia.
Lancet (London, England)
|May 11, 1991
まとめ
大規模な腹部外科手術は,一部の患者の胆石形成を加速する可能性があります. 年齢と手術が重要な要因で,手術後3年以内に胆石を発症する人の割合は28%であった.
科学分野:
- 胃腸内科 胃腸内科
- 肝臓病理学 肝臓病理学
- 外科手術の結果について
背景:
- 胆石 (コレリチアシス) は多因子の病因性で一般的です.
- 大規模な腹部外科手術が胆石の発生に与える影響は,完全に解明されていません.
研究 の 目的:
- 大規模な腹部外科手術と新しい胆石形成の発生率の関連性を調査する.
- 手術後の胆石の発症の臨床的決定因子を特定する.
主な方法:
- 連続腹部超音波検査を平均36ヶ月間受けた73人の患者の遡及的分析.
- 大規模な腹部外科手術を受けた患者と,手術を受けなかった患者の間での胆石発生率の比較.
主要な成果:
- 大規模な腹部手術を受けた47人の患者のうち12人 (25.5%) が,手術後14~36ヶ月以内に胆石を発症した.
- 26人の対照群の患者で新しい胆石は認められませんでした.
- 手術後3年以内に新しい胆石の累積的な罹患率は28%でした.
結論:
- 大規模な腹部外科手術は,急激な胆石発達の重要なリスク因子であるようです.
- 年齢と大きな腹部外科手術は,追跡中の胆石形成の重要な臨床的決定因子です.
- 高リスクグループを特定し,予防対策を検討するために,さらなる見通し研究が必要である.
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