dsxプレ-mRNAの性別スプライシングとポリアデニレーションには,in vitroでは特異的にtra-2タンパク質に結合する配列が必要です

関連する実験動画

Updated: Jul 6, 2026

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins
11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

M L Hedley1, T Maniatis

  • 1Harvard University, Department of Biochemistry and Molecular Biology, Cambridge, Massachusetts 02138.

Cell
|May 17, 1991
PubMed
まとめ

トランスフォーマー-2 (tra-2) タンパク質は,ダブルセックス (dsx) 前mRNAの特定の部位に結合する. この結合は,女性特異のスプライシングとポリアデニレーションに不可欠であり,tra-2がdsxRNA処理を正に調節することを示しています.

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