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Updated: Jul 19, 2026

Mutagenesis and Functional Selection Protocols for Directed Evolution of Proteins in E. coli
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Published on: March 16, 2011

機能性酵素ダイナミクスの移行状態の特徴づけ

Evgenii L Kovrigin1, J Patrick Loria

  • 1Department of Chemistry, Yale University, P.O. Box 208107, New Haven, Connecticut 06520, USA.

Journal of the American Chemical Society
|June 15, 2006
PubMed
まとめ

酵素触媒はタンパク質の動きによって制限されます. 溶媒のデウテリウム含有量は,この運動に影響し,酵素動態の移行状態における単一の陽子の移転を示します.

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