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冠動脈疾患:食事による7つの要因
1AFRC Institute of Food Research, Norwich Laboratory.
Lancet (London, England)
|October 19, 1991
まとめ
冠動脈性心疾患 (CHD) に影響する食事要因は複雑で,脂質仮説によって完全に説明されない. アテロジェニシティとトロンボジェニシティを測定する新しい指数は,多不飽和脂肪と飽和脂肪の比率よりも,CHDのリスクをよりよく予測する可能性があります.
科学分野:
- 栄養科学 栄養科学とは
- 心血管研究に関する研究.
- ダイエットの流行病学
背景:
- 食生活要因は,冠動脈性心疾患 (CHD) の発生率に関与しています.
- 現在の理解は,しばしば脂質仮説に依存しています.
- CHDの促進または保護における特定の食事成分の役割は,微妙な評価を必要とします.
研究 の 目的:
- ダイエット要因と冠動脈疾患 (CHD) を関連付ける証拠をレビューする.
- CHDにおける食事成分の機能的役割を批判的に分析する.
- CHDリスクに対する食事の影響を評価するための代替指標を提案する.
主な方法:
- ダイエットとCHDに関する科学文献の体系的なレビュー.
- 食事要因の保護的または促進的役割に関する証拠の分析.
- 現在の脂質仮説の限界の評価.
主要な成果:
- CHDに対する食事の影響は,脂質仮説が示唆するよりも複雑です.
- 多不飽和脂肪酸と飽和脂肪酸の比率は,食事によるリスクの過度に単純化された尺度である可能性があります.
- 証拠は,より洗練されたインデックスが必要であることを示している.
結論:
- ダイエットと冠動脈疾患の関係は複雑です.
- アテロジェニシティとトロンボジェニシティの指標は,優れた測定値として提案されています.
- 多不飽和度/飽和度比率の置き換えは,心臓病のリスク評価を改善する可能性があります.
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