周周動脈疾患の患者の日常生活中の身体活動と死亡率
Parveen K Garg1, Lu Tian, Michael H Criqui
1New York University School of Medicine, New York City, NY, USA.
Circulation
|July 5, 2006
まとめ
周辺動脈疾患 (PAD) の患者で,より身体的に活発な患者は,より低い死亡率を経験します. 階段を登るなど,より高い毎日の身体活動は,PAD患者の死亡率と心血管疾患の減少に関連しています.
科学分野:
- 心血管の健康について
- ゲロントロジーはゲロントロジーの学科です.
- 運動生理学 運動生理学
背景:
- 周辺動脈疾患 (PAD) は,日常の身体活動レベルと死亡率に影響します.
- PADにおける身体活動と結果の関係を理解することは,患者の管理に不可欠です.
研究 の 目的:
- 外周動脈疾患 (PAD) の患者における毎日の身体活動と死亡率の関連性を調査する.
主な方法:
- PADの患者460人のコホートは57ヶ月間追跡された.
- 身体活動は,インタビューを通じてベースラインで評価され,参加者のサブセットで垂直加速度計を使用して7日間継続的に評価されました.
- 年齢,BMI,高血圧,併発性疾患を含む複数の潜在的な混同要因に調整された統計分析.
主要な成果:
- 加速度計で測定されたより高い身体活動レベルは,すべての原因による死亡率の低下と有意に関連していました (P ((傾向) = 0.003).
- 身体活動の最低四分の一のPAD患者には,最高四分の一の患者と比較して,全死亡リスクが3.48倍増加しました (P=0.019).
- 階段を登る頻度の増加は,全体的な死亡率の減少 (P ((傾向) =0.035) とも関連しており,心血管疾患または死亡率 (P ((傾向) =0.005) で同様の傾向が観察されました.
結論:
- PAD患者における日々の身体活動の増加は,独立して死亡率の低下と心血管疾患の減少と関連しています.
- これらの発見は,身体活動の促進がPAD患者の生存率を向上させることを示唆しています.
- PADにおける生存率の向上のために,日々の身体活動を増やすことを目的とした介入の有効性を調べるために,さらなる研究が必要である.
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