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Updated: May 3, 2026

Characterizing the Composition of Molecular Motors on Moving Axonal Cargo Using "Cargo Mapping" Analysis
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貨物結合ドメインは,ミオシン5の構造と活動を調節する

Kavitha Thirumurugan1, Takeshi Sakamoto, John A Hammer

  • 1Institute of Molecular and Cellular Biology, and Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK.

Nature
|July 14, 2006
PubMed
まとめ

運動タンパク質であるミオシン5は,荷物なしで折りたたまれ,不活性のままです. その球状尾領域 (GTDs) は運動領域に結合し,貨物が存在するまでアクチン相互作用を抑制します.

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