腎臓置換療法を受けているパラレジック患者の膀腫瘍
M Yaqoob1, P McClelland, G M Bell
1Royal Liverpool University Hospital, UK.
Lancet (London, England)
|December 21, 1991
まとめ
透析を受けている神経性膀の患者は,尿道膀腫瘍のリスクが高い. このリスクを軽減するために,腎臓移植前に定期的に泌尿器科のスクリーニングと潜在的なシステクトミーを行うことが推奨されます.
科学分野:
- ネフロロジーはネフロロジーを用います.
- 泌尿器科 泌尿器科とは
- 腫瘍学 腫瘍学
背景:
- 末期腎疾患 (ESRD) は,神経性膀の患者の場合,しばしば脊髄分裂症または脊髄損傷によるもので,定期的な血液透析を必要とします.
- これらの患者はまた,腎臓移植を受けることもあります.
- この特定の集団における尿道膀腫瘍のリスクは十分に確立されていません.
研究 の 目的:
- ヘモダイアリスを受けた神経原発性膀に二次的なESRDを有する成人の患者における尿道膀腫瘍の発生率を調査する.
- 腎臓移植を受けた患者におけるこれらの腫瘍の発生を評価する.
主な方法:
- ニューロゲン性膀によるESRDを患った成人患者14人のコホートを追跡した.
- 患者は,平均20ヶ月間,定期的に血液透析を受けた.
- 7人の患者が腎臓移植を受け,泌尿器官の状態をモニタリングした.
主要な成果:
- 14人の患者のうち4人 (28.6%) が尿道腫瘍を発症した.
- 3例の状細胞癌は,透析中の患者で発生しました.
- 1つの差異性の過渡性細胞癌は,移植後の患者で診断されました.
- 4人の患者全員が,広範囲に広がった転移性疾患を発症し,診断から8週間以内に死亡しました.
結論:
- 透析中の神経性膀の患者は,尿道膀腫瘍を発症する重大なリスクがあります.
- 定期的な泌尿器科の評価は,透析を開始した後でも,これらの患者にとって非常に重要です.
- 腎臓移植前の予防的全囊切除術は,これらの珍しいが攻撃的な腫瘍のリスクを軽減する可能性があります.
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