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Updated: Jul 31, 2026

In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila
13:21

In Vivo Biosensor Tracks Non-apoptotic Caspase Activity in Drosophila

Published on: November 27, 2016

オートファギーのp53誘発モデュレータであるDRAMは,アポトーシスの決定的な役割を果たしています

Diane Crighton1, Simon Wilkinson, Jim O'Prey

  • 1Tumour Cell Death Laboratory, Beatson Institute for Cancer Research, Cancer Research UK Beatson Laboratories, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK.

Cell
|July 15, 2006
PubMed
まとめ

腫瘍抑制剤p53は,新しい自己死調節体であるDRAMを介してプログラム細胞死を誘発する. DRAMはp53-mediated apoptosisに不可欠であり,野生型p53.3を持つ腫瘍ではしばしばダウンレギュレーションされる.

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Knockdown of FAM83A to Verify Its Role in Cervical Cancer Cell Growth and Cisplatin Sensitivity04:20

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