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Updated: May 11, 2026

Monitoring Dynamic Changes In Mitochondrial Calcium Levels During Apoptosis Using A Genetically Encoded Calcium Sensor
06:26

Monitoring Dynamic Changes In Mitochondrial Calcium Levels During Apoptosis Using A Genetically Encoded Calcium Sensor

Published on: April 1, 2011

ミトコンドリアのロンボイド型PARLは,OPA1依存の結晶の改造を通じて,アポトーシス中にシトクロームcの放出を調節する

Sara Cipolat1, Tomasz Rudka, Dieter Hartmann

  • 1Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, Padova, Italy.

Cell
|July 15, 2006
PubMed
まとめ

プレセニリン関連ロンボイド型 (PARL) タンパク質は,アポトーシスの予防に不可欠なミトコンドリアタンパク質であるOPA1の処理に不可欠です. PARL欠乏症は,プログラム細胞死亡の増加により,マウスのマルチシステム縮と死亡につながる.

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