発症率,原因,および短期的な結末は,幼児期における性状態のエピレプシス:将来的な人口ベースの研究
Richard F M Chin1, Brian G R Neville, Catherine Peckham
1Neurosciences Unit, Institute of Child Health, University College London, and Great Ormond Street Hospital for Children NHS Trust, London, UK. r.chin@ich.ucl.ac.uk
Lancet (London, England)
|July 18, 2006
まとめ
幼児の性状態の (CSE: Childhood convulsive status epilepticus) は,ユニークな小児学的側面を持つ一般的な緊急事態である. この研究では,CSEは子供では成人に比べてより頻繁に発生し,死亡率も低いことが判明し,よりよい管理を促しています.
科学分野:
- 小児神経学について
- エピデミオロジー エピデミオロジー
- 緊急医療 緊急医療
背景:
- 発作状態の (CSE:convulsive status epilepticus) は,主要な小児神経学的緊急事態である.
- 主に成人の集団から得られた既存のデータは,子供のCSEを正確に反映していない可能性があります.
- ノース・ロンドン・ステータス・エピレプシス・イン・チャイルドフッド・サーベイランス・スタディ (NLSTEPSS) は,小児の視点を提供するために開始されました.
研究 の 目的:
- 幼児期のCSEの発生率と特徴を決定する.
- CSEのユニークな小児学的な理解を確立する.
- 臨床管理と小児CSEのためのリソースの割り当てを伝えるために.
主な方法:
- ロンドン北部の将来的な,人口ベースの監視研究.
- 標準化されたプロフォームと医療記録を使用して,臨床ネットワークを通じて収集されたデータ.
- 確認を推定するために使用されるキャプチャ-再キャプチャモデリング.
主要な成果:
- CSEエピソードの推定確定率は62%から84%です.
- 毎年10万人に17〜23回の発生率で,確認に調整された.
- 1年間の再発率は16%で,死亡率は3%です.
結論:
- 幼児期のCSEは,成人に比べてより一般的で致命的ではない.
- 小児CSEの原因は,成人集団と異なる.
- 小児のデータは,CSEの効果的な管理とリソースの配分に不可欠です.
関連する概念動画
Longitudinal Research
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
Regression Toward the Mean
Regression toward the mean (“RTM”) is a phenomenon in which extremely high or low values—for example, and individual’s blood pressure at a particular moment—appear closer to a group’s average upon remeasuring. Although this statistical peculiarity is the result of random error and chance, it has been problematic across various medical, scientific, financial and psychological applications. In particular, RTM, if not taken into account, can interfere when researchers try to extrapolate results...
Meiosis vs. Mitosis
Cell division is necessary for growth and reproduction in organisms. Mitosis aids cell growth and development by dividing somatic cells. In contrast, meiosis causes the division of germ cells and plays an essential role in sexual reproduction. Due to their unique functional requirements, mitosis and meiosis differ from each other in multiple aspects.
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Psychosexual Stages of Personality: Latency
Following the phallic stage in Freud's theory of psychosexual development, children enter a phase called the latency period, which lasts from approximately six to twelve years of age. Unlike earlier stages, where sexual impulses played a central role, Freud believed these impulses are repressed during the latency period, becoming part of the unconscious. This stage is often described as a time of psychological calm after the turbulence of the phallic stage.
The latency period is not considered...
The latency period is not considered...
Psychosexual Theory of Development
Sigmund Freud's psychosexual theory of development suggests that early childhood experiences significantly shape personality and behavior. Freud proposed that development is discontinuous, occurring in five distinct stages, each defined by a focus on different erogenous zones. He believed that failure to resolve the conflicts specific to each stage successfully could result in fixation, potentially influencing behavior as adults.
The Five Stages of Psychosexual Development
Freud's psychosexual...
The Five Stages of Psychosexual Development
Freud's psychosexual...
Psychological and Sociocultural Causes of Schizophrenia
Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...


