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Updated: Jul 13, 2026

Enrichment of Bruch's Membrane from Human Donor Eyes
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Enrichment of Bruch's Membrane from Human Donor Eyes

Published on: November 15, 2015

補完因子H多形化,補完活性化,および年齢関連の黄斑変性障害のリスク

Dominiek D G Despriet1, Caroline C W Klaver, Jacqueline C M Witteman

  • 1Department of Epidemiology and Biostatistics, Erasmus Medical Center, Rotterdam, The Netherlands.

JAMA
|July 20, 2006
PubMed
まとめ

補足因子H (CFH) Y402H遺伝子の変異は,特に炎症とともに,年齢関連の黄斑変性 (AMD) のリスクを大幅に増加させます. この遺伝的要因は,特に喫煙や高濃度のC反応性タンパク質 (CRP) と組み合わせると,AMDの流行に大きく寄与します.

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