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Updated: Jul 11, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

Rab GTPasesのTBCドメインのGAPは,双指メカニズムでGTPの水解を加速する

Xiaojing Pan1, Sudharshan Eathiraj, Mary Munson

  • 1Program in Molecular Medicine & Department of Biochemistry and Molecular Pharmacology, UMASS Medical School, Two Biotech, 373 Plantation Street, Worcester, Massachusetts 01605, USA.

Nature
|July 21, 2006
PubMed
まとめ

GTPase活性化タンパク質 (GAPs) は,RabのGTPase活性を調節する. この研究では,TBCドメインのGAPが,GTP水解を加速するために,アルジニンとグルタミンを含む二指メカニズムを使用して,以前の予想とは異なることを明らかにしました.

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Comparing the Affinity of GTPase-binding Proteins using Competition Assays10:37

Comparing the Affinity of GTPase-binding Proteins using Competition Assays

Published on: October 8, 2015

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay13:51

Detection of Small GTPase Prenylation and GTP Binding Using Membrane Fractionation and GTPase-linked Immunosorbent Assay

Published on: November 11, 2018

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