アルキンの転解のための高度に活性なモリブデン-アルキリジンの触媒:アルキンと転解することによって,窒素から合成
Robyn L Gdula1, Marc J A Johnson
1Department of Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, USA.
Journal of the American Chemical Society
|July 27, 2006
まとめ
新しいモリブデンニトリド複合体は,3-ヘクシンと反応してプロピリジン複合体を形成する. これらの複合体は,アドクトの便利な分離により,アルキンの転移反応の触媒として知られています.
科学分野:
- 有機金属化学 有機金属化学
- カタリシス カタリシス カタリシス
背景:
- モリブデンニトリド複合体は,窒素移転反応における重要な中間物質である.
- アルキンメタテシスは,炭素-炭素結合形成のための強力なツールです.
研究 の 目的:
- 内部アルキンと新しいモリブデンニトリド複合体の反応性を調査する.
- これらの反応から派生したプロピリジン複合体を合成し,特徴づけること.
- アルキンメタテシス触媒の前駆体としてのこれらの複合体の有用性を探求する.
主な方法:
- 末端ニトリド複合体の反応は,高温で3-ヘクシンと反応する.
- 結果となるプロピリジン複合体の分離と特徴付け.
- 1,2-ジメトキシエタン (DME) の形成は,結晶化の改善を誘導する.
主要な成果:
- ニトリド複合体のNMo(OC(CF3) 2Me) 3 ,NMo(OC(CF3) 2Me) 3 ,NCMe ,およびNMo(OC(CF3) 3 ,NCMe) が3-ヘクシンと不可逆的に反応する.
- プロピリジン複合体の形成 EtCMo (((OC (((CF3) 2Me) 3と EtCMo (((OC ((CF3) 3) 3) 3.3.
- プロピリジン複合体をDMEアダクトとして便利に分離し,マルチグラムスケールで3DMEの61%の収量を得ました.
結論:
- モリブデンニトリド複合体は,プロピリジン複合体の効果的な前駆体として機能する.
- 合成されたプロピリジン複合体は容易に分離可能であり,アルキンの転移において潜在的に有用である.
- この研究は,既知の,高度に活性なアルキンメタテシス触媒への便利な経路を提供します.
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