遺伝子調節におけるシスとトランスの曖昧さ
Fabio Savarese1, Rudolf Grosschedl
1Max Planck Institute of Immunobiology, 79108 Freiburg, Germany.
Cell
|July 29, 2006
まとめ
単一の増強剤は複数のオロラント受容体 (OR) 遺伝子を制御することができ,嗅覚感覚ニューロンが1000以上の遺伝子からたった1つの遺伝子を選択する方法を説明します. この発見は,嗅覚受容体の遺伝子発現の複雑なメカニズムに光を当てています.
科学分野:
- 遺伝学 遺伝学とは
- 神経科学は神経科学である.
- 分子生物学は分子生物学である.
背景:
- 嗅覚センサーニューロン (OSN) は,1000以上の嗅覚受容体 (OR) 遺伝子の膨大なレパートリーを表現しています.
- 単一のOR遺伝子のモノアレル発現を達成するOSNの正確なメカニズムは,嗅覚研究における重要な問題です.
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