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Updated: Jul 5, 2026

Selective Cell Elimination from Mixed 3D Culture Using a Near Infrared Photoimmunotherapy Technique
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Published on: March 14, 2016

人間のIRGMは,細胞内ミコバクテリアを排除するためにオートファギーを誘発します

Sudha B Singh1, Alexander S Davis, Gregory A Taylor

  • 1Department of Molecular Genetics and Microbiology, University of New Mexico School of Medicine, Albuquerque, NM 87131, USA.

Science (New York, N.Y.)
|August 5, 2006
PubMed
まとめ

ネズミのIrgm1やヒトのIRGMのような免疫関連のGTPases (IRGs) は,細胞内Mycobacterium tuberculosisを排除するためにオートファギーを促進し,バクテリアの負荷を減らす.

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The innate immune response is an immediate and non-specific response against pathogens, acting swiftly to prevent the spread of infections. The primary cells involved in this response are phagocytes and natural killer (NK) cells.
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Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
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iChip

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Introduction to the Human Microbiota

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