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Updated: Jun 26, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

(-) - および ent-(+) - ヴィンドリンおよび関連するアルカロイドの総合成

Hayato Ishikawa1, Gregory I Elliott, Juraj Velcicky

  • 1Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Journal of the American Chemical Society
|August 10, 2006
PubMed
まとめ

新しいタンデム・サイクロアディションを用いて,11段階のヴィンドリンエナントオメア合成が達成されました. この効率的な方法は,ペンタサイクルのコアを迅速に構築し,ステレオセンターを設定し,重要な機能を1つのステップで導入します.

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