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Updated: Jul 20, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

HIVエンベロープのグリコタンパク質,抗原特異のT細胞応答,および溶解性CD4

F Manca1, J A Habeshaw, A G Dalgleish

  • 1Department of Immunology, University of Genoa, San Martino Hospital, Italy.

Lancet (London, England)
|April 7, 1990
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) が抗原を呈現する細胞からT細胞に移転すると,T細胞が死亡する. 溶解性gp120はT細胞の増殖を阻害し,gp120/CD4の相互作用がHIVの病原性の鍵であることを示唆しています.

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