単一のCH/piの弱い水素結合が,光活性黄色タンパク質の安定性と光サイクルを制御する

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Updated: Jul 14, 2026

FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation
08:31

FM Dye Cycling at the Synapse: Comparing High Potassium Depolarization, Electrical and Channelrhodopsin Stimulation

Published on: May 24, 2018

Miki Harigai1, Mikio Kataoka, Yasushi Imamoto

  • 1Graduate School of Materials Science, Nara Institute of Science and Technology, Ikoma Nara 630-0192, Japan.

Journal of the American Chemical Society
|August 17, 2006
PubMed
まとめ

CH/piの相互作用は,光活性黄色タンパク質 (PYP) の機能に不可欠である. Phe6やLys123のような重要な残基の変異は,この弱い相互作用を妨害し,重要なタンパク質の機能障害を引き起こす.

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