関連する実験動画

Updated: Jul 10, 2026

Environmentally Induced Heritable Changes in Flax
08:10

Environmentally Induced Heritable Changes in Flax

Published on: January 26, 2011

性線維症遺伝子のフレームシフト変異である

M B White1, J Amos, J M Hsu

  • 1Laboratory of Viral Carcinogenesis, National Cancer Institute, Frederick, Maryland 21701.

Nature
|April 12, 1990
PubMed
まとめ

囊性線維症 (CF) は,CFTR遺伝子変異によって引き起こされる遺伝疾患です. 研究者らは,CFファミリーにおける新しい変異を特定し,非機能的なタンパク質につながり,CFにおける遺伝的多様性を強調した.

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Genetic Modification of Cyanobacteria by Conjugation Using the CyanoGate Modular Cloning Toolkit08:25

Genetic Modification of Cyanobacteria by Conjugation Using the CyanoGate Modular Cloning Toolkit

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関連する概念動画

Mutations01:39

Mutations

Overview
Mutations01:39

Mutations

Overview
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
Mutations01:35

Mutations

Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
Chromosomal Alterations Are Large-Scale Mutations
While point mutations are changes in a single nucleotide in...
Gene Conversion02:08

Gene Conversion

Other than maintaining genome stability via DNA repair, homologous recombination plays an important role in diversifying the genome. In fact, the recombination of sequences forms the molecular basis of genomic evolution. Random and non-random permutations of genomic sequences create a library of new amalgamated sequences. These newly formed genomes can determine the fitness and survival of cells. In bacteria, homologous and non-homologous types of recombination lead to the evolution of new...
Point and Frameshift Mutations01:30

Point and Frameshift Mutations

Point mutations are genetic alterations involving the change of a single nucleotide base pair in DNA. Depending on how the alteration affects protein synthesis, they can lead to various consequences.Point mutations fall into the following types:Silent mutations occur when a nucleotide change does not alter the amino acid sequence due to the redundancy of the genetic code. For instance, changing ACC to ACA still encodes threonine, leaving the protein function unaffected. This occurs because...