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喫煙と52か国における心筋梗塞のリスク,INTERHEART研究:ケース・コントロール研究
Koon K Teo1, Stephanie Ounpuu, Steven Hawken
1Population Health Research Institute, McMaster University-Hamilton Health Sciences, Hamilton, ON L8L 2X2, Canada.
Lancet (London, England)
|August 22, 2006
まとめ
タバコの使用は,喫煙やを含む,急性心筋梗塞 (AMI) のリスクを大幅に増加させます. 二手喫煙 (SHS) を含むすべての形のタバコの使用を抑止することは,世界的に心血管疾患の予防に不可欠です.
科学分野:
- 心血管伝染病学 心血管伝染病学
- タバコ規制研究 研究
- 公衆衛生は公衆衛生である.
背景:
- タバコの使用は,世界中で心血管疾患の主要な予防可能な原因です.
- さまざまなタバコ製品と二手喫煙による世界的なリスクを評価することは極めて重要です.
研究 の 目的:
- 様々な種類のタバコ使用 (喫煙,無煙タバコ,二手喫煙) と急性心筋梗塞 (AMI) のリスクとの関連性を評価する.
主な方法:
- 52カ国の27,089人の参加者を対象とした標準化されたケース・コントロール研究です.
- 現在の/以前の喫煙,タバコの種類,数量,無煙タバコ,およびSHS暴露に関連するリスクの評価.
- 喫煙者と非喫煙者のライフスタイルの混同因子に制御された.
主要な成果:
- 現在の喫煙は,致命的でないAMIのリスクを有意に増加させた (OR2.95);リスクは,タバコの消費で上昇した.
- 元喫煙者は,禁煙から20年経っても残留リスクを抱えていた.
- チューインタバコ (OR 2.23) とSHS暴露 (OR 1.24-1.62) も,AMIのリスクが高かった.
- 若い男性は,喫煙による人口の関連リスクが最も高く,SHSは,決して喫煙していない人にとって重大なリスクをもたらしました.
結論:
- あらゆる形態のタバコの使用は,特に男性において,AMIの主要な世界的な要因である.
- 心血管疾患の予防には,喫煙,タバコ,SHSへの曝露を抑止することが不可欠です.
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