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Updated: Jul 24, 2026

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events
10:59

Artificial RNA Polymerase II Elongation Complexes for Dissecting Co-transcriptional RNA Processing Events

Published on: May 13, 2019

トランスドミナントRNAポリメラーゼ変異によって,イニシアーションから延長への移行をブロックする

M Kashlev1, J Lee, K Zalenskaya

  • 1Institute of Molecular Genetics, U.S.S.R. Academy of Sciences, Moscow.

Science (New York, N.Y.)
|May 25, 1990
PubMed
まとめ

Escherichia coliのRNAポリメラーゼの突然変異は,DNAの延長を防ぐことによって遺伝子発現を妨害する. この変異酵素は細胞の成長を阻害し,プロモーターへのワイルド型ポリメラーゼのアクセスを阻害します.

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