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Updated: Jul 15, 2026

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study
11:10

Antibody Binding Specificity for Kappa (Vκ) Light Chain-containing Human (IgM) Antibodies: Polysialic Acid (PSA) Attached to NCAM as a Case Study

Published on: June 29, 2016

共有ヒトT細胞受容体Vβの使用は,ミエリン基質タンパク質の免疫支配領域に共通しています

K W Wucherpfennig1, K Ota, N Endo

  • 1Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115.

Science (New York, N.Y.)
|May 25, 1990
PubMed
まとめ

研究者らは,多発性硬化症 (MS) の患者で共有されたT細胞受容体 (TCR) Vベータ遺伝子使用が,ミエリン基本タンパク質 (MBP) を認識することを発見しました. この発見は,MS治療のための特定のTCR構造を標的とした新しい免疫療法につながる可能性があります.

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