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Updated: Jul 13, 2026

Streamlined Single Cell TCR Isolation and Generation of Retroviral Vectors for In Vitro and In Vivo Expression of Human TCRs
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Published on: September 10, 2017

CTLA-4によるTCR停止信号の逆転

Helga Schneider1, Jos Downey, Andrew Smith

  • 1Cell Signalling Section, Division of Immunology, Department of Pathology, University of Cambridge, Cambridge CB2 1QP, UK.

Science (New York, N.Y.)
|August 26, 2006
PubMed
まとめ

細胞毒性Tリンパ球関連抗原4 (CTLA-4) は,T細胞の動きを高め,T細胞受容体シグナリングを減少させます. このメカニズムは免疫細胞の活性化値を下げ,潜在的に自己免疫疾患を予防します.

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