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Updated: Jul 6, 2026

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

シクリン依存キナーゼ阻害剤p16INK4aによって改変された幹細胞の老化

Viktor Janzen1, Randolf Forkert, Heather E Fleming

  • 1Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, Massachusetts 02114, USA.

Nature
|September 8, 2006
PubMed
まとめ

幹細胞の老化は組織修復に影響する. 造血幹細胞 (HSC) のp16INK4aを阻害することで,その機能とストレス耐性を改善し,年齢関連の衰退と闘う潜在的な戦略を提供した.

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