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Updated: May 3, 2026

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation
09:37

A RANKL-based Osteoclast Culture Assay of Mouse Bone Marrow to Investigate the Role of mTORC1 in Osteoclast Formation

Published on: March 15, 2018

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SIN1/MIP1はリクター-mTOR複合体の完全性を維持し,アクトのリン酸化と基板特異性を調節する

Estela Jacinto1, Valeria Facchinetti, Dou Liu

  • 1Department of Physiology and Biophysics, UMDNJ-Robert Wood Johnson Medical School, Piscataway, NJ 08854, USA.

Cell
|September 12, 2006
PubMed
まとめ

SIN1はmTORC2の重要なサブユニットで,Akt Ser473のリン酸化と細胞生存に不可欠です. その欠如はTORC2の機能を妨げますが,TORC1の機能は妨げず,FoxO1/3a.のような特定のAktのターゲットに影響します.

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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method08:04

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Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity07:09

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