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Updated: Jul 19, 2026

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
11:48

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Published on: May 31, 2018

LFA-3,CD44,CD45:ヒト単細胞TNFとIL-1の放出の生理学的トリガーである

D S Webb1, Y Shimizu, G A Van Seventer

  • 1Food and Drug Administration, Division of Cytokine Biology, Bethesda, MD 20892.

Science (New York, N.Y.)
|September 14, 1990
PubMed
まとめ

LFA-3,CD44,CD45のようなモノサイトグリコプロテインが活性化すると,免疫調節性サイトカインである腫瘍死滅因子αとインタールイキン-1βの放出を誘発する. これは,細胞粘着相互作用がモノカインの放出をシグナルすることを示唆しています.

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