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Updated: May 1, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 29, 2010

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リンチ症候群におけるMLH1およびMSH2変異の予測

Judith Balmaña1, David H Stockwell, Ewout W Steyerberg

  • 1Population Sciences Division, Dana-Farber Cancer Institute, and Division of Gastroenterology, Boston, Mass 02115, USA.

JAMA
|September 28, 2006
PubMed
まとめ

MLH1/MSH2遺伝子のリンチ症候群変異は,リスクの高い患者で一般的です. PREMM ((1,2) モデルは,個人および家族のがん歴を使用して変異の可能性を正確に予測し,遺伝子検査戦略を支援します.

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