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Updated: Jul 12, 2026

High-throughput Yeast Plasmid Overexpression Screen
08:57

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Published on: July 27, 2011

フロントテンポラルロバー変性およびアミオトロフィック横筋硬化症におけるウビキチン化TDP-43

Manuela Neumann1, Deepak M Sampathu, Linda K Kwong

  • 1Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|October 7, 2006
PubMed
まとめ

TDP-43タンパク質は,前頭側頭葉変性および筋縮性横筋硬化症における主要な病理学的マーカーである. このタンパク質は高リン酸化され,脳と脊髄の損傷した領域に存在し,これらの神経変性疾患を結びつけています.

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