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Updated: Jul 19, 2026

Profiling Voltage-gated Potassium Channel mRNA Expression in Nigral Neurons using Single-cell RT-PCR Techniques
07:31

Profiling Voltage-gated Potassium Channel mRNA Expression in Nigral Neurons using Single-cell RT-PCR Techniques

Published on: September 27, 2011

デンドライトにおけるKv1.1チャンネルmRNA翻訳の活動およびmTOR依存抑制

Kimberly F Raab-Graham1, Patrick C G Haddick, Yuh Nung Jan

  • 1Howard Hughes Medical Institute, Departments of Physiology and Biochemistry, University of California, San Francisco, CA 94158, USA.

Science (New York, N.Y.)
|October 7, 2006
PubMed
まとめ

哺乳類のラパミシン (mTOR) 経路の標的の抑制は,海馬の神経 dendrites で Kv1.1 カリウムチャネル発現を高める. これは,シナプス刺激が dendritic Kv1 チャンネルを抑制し,その局所的合成を減少させることを示唆しています.

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