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神経変性における細胞内タンパク質分解経路の役割について

David C Rubinsztein1

  • 1Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.dcr1000@hermes.cam.ac.uk

Nature
|October 20, 2006
PubMed
まとめ

パーキンソン病のような神経変性疾患における有毒なタンパク質集積は,タンパク質分解の障害と関連しています. マクロオートファギーの強化は,これらの状態の治療戦略を提供することができます.

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