Mg-ケラターゼHサブユニットは,アブシシス酸受容体である
Yuan-Yue Shen1, Xiao-Fang Wang, Fu-Qing Wu
1China State Key Laboratory of Plant Physiology and Biochemistry, China Agricultural University, 100094 Beijing, China.
Nature
|October 20, 2006
まとめ
植物で特定されたアブシシ酸受容体 (ABAR/CHLH) は,特にABA.に結合する. このタンパク質は,ストモタ運動と種子発芽を含む重要な植物成長と発達プロセスを調節します.
科学分野:
- 植物生物学 植物生物学
- 分子生物学は分子生物学である.
- バイオケミストリー バイオケミストリー
背景:
- アブシシ酸 (ABA) は,口腔の開口と種子の発達を調節する重要な植物ホルモンです.
- これらの重要な生理学的プロセスを媒介する特定のABA受容体は,ほとんど特定されていないままです.
研究 の 目的:
- 植物におけるABAシグナル伝達を媒介するABA受容体を特定し,特徴づけること.
- CHLHによってコードされるABA結合タンパク質 (ABAR) が,植物の発達とABA認識における役割を明らかにする.
主な方法:
- アラビドプシスABAR/CHLHのABAへの特定の結合を確認するためのABA結合測定法.
- 種子発芽,発芽後の成長,口腔の動きなどの植物生理学的プロセスにおけるABAR/CHLH機能の分析.
- 様々な植物組織におけるABAR/CHLHの表現分析.
主要な成果:
- アラビドプシス (Arabidopsis) ABAR/CHLHは,アブシシ酸を特異的に結合することが確認されました.
- ABAR/CHLHは,種子発芽,発芽後の成長,および口腔の動きのポジティブレギュレータとして作用し,ABA受容体としての役割を確認しています.
- ABAR/CHLHは,緑の組織と非緑の組織の両方で無所不在な発現を示し,植物全体のABA信号認識を示唆しています.
結論:
- ABA結合タンパク質のABAR/CHLHは,アラビドプシスの本来のABA受容体として機能する.
- ABAR/CHLHは,様々な植物発達段階と組織におけるABA反応を媒介する重要な役割を果たします.
- ABAR/CHLHのいたるところに存在する発現は,植物全体のABA信号の知覚と統合のためのその可能性を強調しています.
関連する概念動画
Ligand-gated Ion Channels
11.4K
Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that...
11.4K
Cell Signaling in Plants
4.6K
Plant cells communicate to coordinate their cycle of growth, flowering and fruiting, and activities in roots, shoots, and leaves in response to the changing environmental conditions. Plant signaling is distinct from animal signaling. Plants primarily utilize enzyme-linked receptors, whereas the largest class of cell-surface receptors in animals are G-protein coupled receptors (GPCRs). Unlike animals, receptor tyrosine kinases are rare in plants. Instead, plants have a diverse class of...
4.6K
Ligand-Gated Ion Channel Receptor: Gating Mechanism
4.6K
Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
4.6K
Cholinergic Receptors: Muscarinic
4.9K
The pharmacological actions of acetylcholine are elicited via its binding to two families of cholinergic receptors or cholinoceptors, namely, muscarinic and nicotinic receptors. Muscarinic receptors are G protein-coupled receptors and have five subtypes, M1–M5. All mAChR subtypes are activated by acetylcholine and blocked by the antagonist, atropine.
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
4.9K
Cholinergic Receptors: Nicotinic
5.4K
Nicotinic receptors are ligand-gated ion channels that are activated by acetylcholine and nicotine. Upon activation, they cause a rapid increase in the permeability of cells to K+, Na+, and Ca2+, followed by depolarization and excitation. They are in the autonomic ganglia, skeletal neuromuscular junction, CNS, and adrenal medulla.
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
There are two types of nicotinic receptors: neuromuscular (NM/NM/N1) and neuronal (NN/NN/N2). The two families differ based on their location and selectivity to...
5.4K
Chemotaxis in E. coli
1.4K
Chemotaxis in Escherichia coli is a sensory-driven motility mechanism that enables bacteria to navigate chemical gradients, moving toward beneficial environments while avoiding harmful conditions. This process relies on a signal transduction system integrating external chemical cues with flagellar motor control.Chemoreceptors and Signal DetectionE. coli detects chemical gradients through methyl-accepting chemotaxis proteins (MCPs), which are membrane-bound chemoreceptors that sense attractants...
1.4K


