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Updated: Jun 3, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

レドックス調節は,抗原処理中にMHCクラスIによる最適なペプチド選択を促進します

Boyoun Park1, Sungwook Lee, Eunkyung Kim

  • 1Department of Biological Sciences, National Creative Research Center for Antigen Presentation, Seoul National University, Seoul 151-747, South Korea.

Cell
|October 24, 2006
PubMed
まとめ

タンパク質二硫化イソメラーゼ (PDI) は,MHCクラスIの分子を安定させ,T細胞が感染した細胞を認識することを可能にします. ヒューマン・サイトメガロウイルスは,PDIを劣化させ,PDIを強調することによって,このプロセスを阻害します.

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