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Updated: Jul 17, 2026

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
09:40

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

A PARACESTのMRIコントラスト剤は,酵素活性を検出する

Byunghee Yoo1, Marty D Pagel

  • 1Department of Biomedical Engineering, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106-7207, USA.

Journal of the American Chemical Society
|October 26, 2006
PubMed
まとめ

研究者はMRI用スマートコントラスト剤を開発し,カスパース3を検出し,これはアポトーシスの重要なバイオマーカーである. この薬剤は,カスパース-3の活動によって磁気共鳴信号を変化させ,プログラムされた細胞死亡の感度のある検出を可能にします.

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