関連する実験動画

Updated: May 7, 2026

Identification of Kinase-substrate Pairs Using High Throughput Screening
11:13

Identification of Kinase-substrate Pairs Using High Throughput Screening

Published on: August 29, 2015

受容体チロシンキナーゼ,中間T/pp60c-src複合体,PI3-キナーゼと結合する2つの85 kdタンパク質の特徴化

M Otsu1, I Hiles, I Gout

  • 1Ludwig Institute for Cancer Research, London, England.

Cell
|April 5, 1991
PubMed
まとめ

牛の脳フォスファティディルノシトール3キナーゼ (PI3キナーゼ) は,SH2ドメインを持つ85kDaのタンパク質 (p85α/β) を含む. これらのタンパク質はチロシンキナーゼと結合するが,PI3-キナーゼの活性がないため,シグナル伝達経路の調節作用が示唆される.

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