長期旅行者のマラリア予防
Lin H Chen1, Mary E Wilson, Patricia Schlagenhauf
1Travel Medicine Center, Division of Infectious Diseases, Mount Auburn Hospital, Cambridge, Mass 02238, USA. lchen@hms.harvard.edu
JAMA
|November 9, 2006
まとめ
長期旅行者は,より高いマラリアリスクに直面し,多くの場合,保護措置を過小評価します. 化学予防と個人保護を含む個別の予防戦略は,長期的なマラリア予防に不可欠です.
科学分野:
- 旅行 医療 医療
- 感染症 感染症は感染症です.
- トロピカル・メディシン (熱帯医学)
背景:
- 長期旅行者 (≥6ヶ月) は,マラリア予防のユニークな課題に直面します.
- 既存のガイドラインは,主に短期旅行者とPlasmodium falciparum.に重点を置いています.
- 長い旅のマラリア予防には,特別な注意が必要です.
研究 の 目的:
- 長期旅行者のマラリアリスクを評価するために.
- 個人保護措置の進展をレビューする.
- 長期的なマラリア化学予防の安全性と有効性を評価し,P. vivax再発予防を含む予防戦略を探求する.
主な方法:
- 2006年7月までの科学出版物 (MEDLINE,PubMed) の包括的な文献検索を行いました.
- 長期旅行,マラリア予防,化学予防,昆虫駆除剤に関する研究を含む.
- 言語の制限なく,文献,論文,会議の議事録から得られた追加データ.
主要な成果:
- 長期旅行者は,短期旅行者と比較してマラリアのリスクが高くなります.
- 個人保護措置の不足と,化学予防療法への不十分な遵守が指摘されています.
- 各々のメリット・デメリットを持つ様々な戦略が存在し,偽造薬は大きな懸念事項であり,P. vivaxの再発は現在の第一線療法では予防できない.
結論:
- 長期旅行者のマラリア予防は複雑で,専門の旅行医療の相談が必要である.
- 個別化された勧告は,この人口集団における効果的なマラリア予防に不可欠です.
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