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Updated: Jul 16, 2026

Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes
07:26

Single-molecule Super-resolution Imaging of Phosphatidylinositol 4,5-bisphosphate in the Plasma Membrane with Novel Fluorescent Probes

Published on: October 15, 2016

PI(3,4,5) P3とPI(4,5) P2の脂質は,多塩基のクラスターを持つタンパク質を標的とし,プラズマ膜に届きます

Won Do Heo1, Takanari Inoue, Wei Sun Park

  • 1Department of Molecular Pharmacology, 318 Campus Drive, Clark Building, Stanford University Medical School, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|November 11, 2006
PubMed
まとめ

多くのタンパク質は,多塩基群を用いて,プラズマ膜を標的とする. これらのクラスタは,効果的な血局所化のために,フォスファディチリノシトール4,5-ビスホスファート [PI(4,5) P2]とフォスファディチリノシトール3,4,5-トリスホスファート [PI(3,4,5) P3]の両方を必要とします.

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PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

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Fluorescence-Based Measurements of Phosphatidylserine/Phosphatidylinositol 4-Phosphate Exchange Between Membranes

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