中年のリスク要因と男性における健康的な生存率
Bradley J Willcox1, Qimei He, Randi Chen
1Pacific Health Research Institute, Honolulu, HI 96813, USA. bjwillcox@phrihawaii.org
JAMA
|November 16, 2006
まとめ
肥満,喫煙,高血圧などの危険因子を避けていた中年男性には,全体的な生存率と例外的な生存率がより高くなった. 中年期に健康的な習慣を身につけることは,より長く,より健康的な生活につながります.
科学分野:
- ゲロントロジーと公衆衛生
- エピデミオロジー エピデミオロジー
- 予防医学は,予防的な医療です.
背景:
- 健康的な生存には明確な定義がなく,その属性は,特に男性では,ほとんど理解されていません.
- 長期的な健康状態に影響を与える中年期の要因については,さらなる調査が必要である.
研究 の 目的:
- 中年の生物学的,ライフスタイル,社会人口学的要因と全生存率との関連を調査する.
- 主要な疾患や障害のない高齢まで生きることと定義される例外的な生存に関連する要因を決定する.
主な方法:
- 45歳から68歳の日本系アメリカ人男性5820人を対象に,前向きなコホート研究が行われました.
- 総生存率と例外的な生存率を評価するために,参加者を最大40年間追跡した.
- 特殊な生存期間は,75,80,85,または90歳に達し,6つの主要な慢性疾患および障害から自由であると定義されました.
主要な成果:
- 42%が85歳まで生存し,11%が85歳まで例外的な生存を達成しました.
- 握りの強さが高いこと,肥満,高血糖症,高血圧,喫煙,過剰なアルコール摂取を避けることは,よりよい生存率と関連していた.
- 高等教育と高トリグリセリデミアの回避は,例外的な生存率と関連しており,パートナーの欠如は死亡率のリスクを増加させた.
結論:
- 中年期リスクファクターの回避は,男性における長寿で健康的な生存の可能性の増加と関連しています.
- 累積リスクスコアは,最も高齢の生存率と例外的な生存率を効果的に予測します.
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